3-Methyl-2-butenylboronic acid pinacol ester

3-Methyl-2-butenylboronic acid pinacol ester - Names and Identifiers

Name	3,3-Dimethylallylboronic acid pinacol ester, 2-(3-Methyl-but-2-enyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
Synonyms	3-Methyl-2-butenylboronic acid pinacol ester 3-Methylbut-2-enylboronic acid, pinacol ester 3-Methyl-2-butenylboronic acid pinacol ester 4,4,5,5-tetraMethyl-2-(3-Methylbut-2-enyl)-1,3,2-dioxaborolane 2-(3-Methyl-but-2-enyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 4,4,5,5-Tetramethyl-2-(3-methyl-2-buten-1-yl)-1,3,2-dioxaborolane 4,4,5,5-Tetramethyl-2-(3-methylbut-2-en-1-yl)-1,3,2-dioxaborolane 3,3-Dimethylallylboronic acid pinacol ester, 2-(3-Methyl-but-2-enyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 3,3-Dimethylallylboronic acid pinacol ester, 2-(3-Methyl-but-2-enyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CAS	141550-13-2
InChIKey	QXDMQRNIDKVRCN-UHFFFAOYSA-N

3-Methyl-2-butenylboronic acid pinacol ester - Physico-chemical Properties

Molecular Formula	C11H21BO2
Molar Mass	196.09
Density	0.885g/mLat 25°C
Boling Point	42-45°C/0.6mmHg
Flash Point	77°C
Storage Condition	2-8°C
Refractive Index	n20/D 1.4395

3-Methyl-2-butenylboronic acid pinacol ester - Risk and Safety

UN IDs	NA 1993 / PGIII
WGK Germany	3

3-Methyl-2-butenylboronic acid pinacol ester - Upstream Downstream Industry

Downstream Products

2,2-dimethylbut-3-enoic acid

3-Methyl-2-butenylboronic acid pinacol ester - Introduction

3,3-dimethylallboronic acid pinacol ester, 2-(3-Methyl-but-2-enyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, also known as 3,3-dimethylallboronic acid pinacol ester or 2-(3-methyl-but-2-butl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, is an organic compound.

Nature:
-Appearance: colorless liquid
-Molecular formula: C11H21BO2
-Molecular weight: 194.09g/mol
-Melting point:-5 ℃
-Boiling point: 80-85 ℃
-Density: 0.889 g/mL
-Solubility: Soluble in organic solvents such as ethanol, methanol and dichloromethane

Use:
3,3-dimethylallboronic acid pinacol ester, 2-(3-Methyl-but-2-enyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is mainly used for the cross-coupling reaction of halogenated olefins in organic synthesis, in particular, the palladium-catalyzed Suzuki coupling reaction. It can be introduced into other organic molecules as an inoculant group for the construction of complex organic compounds.

Method:
The preparation of 3,3-dimethylallylboronic acid pinacol ester, 2-(3-Methyl-but-2-enyl)-4,4, 5,5-tetrameyl-1, 3,2-dioxaborolane can be carried out by the following steps:
1. 3-Chloro-2-butene (3-chloroo-2-butene) reacts with triethylamine to generate 3-Methyl-2-butene (3-Methyl-2-butene).
2. The resulting 3-methyl-2-butene was reacted with Pinacolborane or Diboron ester to give 3,3-dimethylallylboronic acid pinacol ester, 2-(3-Methyl-but-2-enyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane.

Safety Information:
3,3-dimethylallylboronic acid pinacol ester, 2-(3-Methyl-but-2-enyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane has low toxicity, but it is still necessary to pay attention to safe operation. During handling and use, the laboratory's safe operating procedures should be followed and appropriate protective measures should be taken, such as wearing protective glasses and gloves. Avoid skin contact and inhalation. If inadvertent contact or misuse, should be promptly washed or seek medical assistance.

Last Update：2024-04-10 22:29:15